Influence of sub-optimal hydration on the immune response
By Dorothée Chabas
Recorded on 23/06/2021
Dorothée Chabas MD PhD is a French American neuro-immunologist, based in San Francisco. She is an expert in adult and pediatric Multiple Sclerosis (MS), an autoimmune disease of the central nervous system. She was the co-founder, co-investigator and co-director of the University of California, San Francisco (UCSF) Regional Pediatric MS Program and is the editor of the first medical textbook focused exclusively on pediatric MS (Demyelinating Disorders of the Central Nervous System in Childhood, Cambridge University Press). Her research at Paris Pitié Salpêtrière University Hospital, Stanford University and then UCSF, has focused on the clinical and immunological aspects of MS. Her most notable contributions to the field of immunology have been about the influence of the pro-inflammatory molecule osteopontin on MS, the description of the central nervous system as a potential effector site of secretory immunity, and the clinical and biological characteristics of MS when it starts in childhood. Her involvement in water research, focusing on immunology, started during the COVID-19 pandemic, when she co-authored an article entitled: Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19 (Stookey et al, Med Hypotheses, 2020 Nov;144:110237).